Robert Nussenblatt,Baoying Liu,Lai Wei,Elazar Rabbani,James J. Donegan
申请号:
US15189531
公开号:
US20160296565A1
申请日:
2016.06.22
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The disclosure relates to methods of identifying a compound that comprises an epitope that induces immune tolerance in a patient suffering from an autoimmune disease. The disclosure further relates to methods of treating an autoimmune disease by administering (i) a compound identified by the methods described herein, (ii) regulatory T-cells from the patient or a compatible donor, or (iii) a combination of regulatory T-cells and a compound identified by the methods described herein. The disclosure further relates to methods of treating age-related macular degeneration and uveitis.