The Trustees of the University of Pennsylvania;Inovio Pharmaceuticals, Inc.
发明人:
Weiner, David,Morrow, Matthew,Wise, Megan
申请号:
AU2016235533
公开号:
AU2016235533B2
申请日:
2016.03.18
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Disclosed is a vaccine comprising an antigen and CD40L, wherein the antigen may be encoded by a first nucleic acid and CD40L may be encoded by a second nucleic acid. Also disclosed are methods for increasing an immune response in a subject, the methods comprise administering the vaccine to the subject in need thereof. Further disclosed is the antigen selected from the group consisting of a human papilloma virus (HPV) antigen, a human immunodeficiency virus (HIV) antigen, an influenza antigen, and a Plasmodium falciparum antigen.