William J. Pitts;James Kempson;Junqing Guo;Hong Wu;Zhonghui Lu;Shuqun Lin;Stephen T. Wrobleski;Jagabandhu Das;Bingwei Vera Yang;Jingwu Duan;Bin Jiang;John Hynes;Steven H. Spergel
发明人:
Stephen T. Wrobleski,Jagabandhu Das,Jingwu Duan,Junqing Guo,John Hynes,Bin Jiang,James Kempson,Shuqun Lin,Zhonghui Lu,William J. Pitts,Steven H. Spergel,Hong Wu,Bingwei Vera Yang
申请号:
US14005568
公开号:
US08987268B2
申请日:
2012.03.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.