Polypeptides and polypeptide constructs comprising single domain antibodies directed against von Willebrand factor

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专利权人:

Karen Silence

发明人:

Karen Silence

申请号：

US10541708

公开号：

US09028816B2

申请日:

2004.01.09

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to polypeptides and polypeptide constructs comprising at least one single domain antibody directed against vWF, vWF A1 domain, A1 domain of activated vWF, vWF A3 domain, homologues of said polypeptides, and/or functional portions of said polypeptides, for the treatment for conditions which require a modulation of platelet-mediated aggregation.

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