Methods for treating a disease involving choroidal neovascularization by administering an IL-6 receptor antibody

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专利权人:

Susumu Ishida

发明人:

Susumu Ishida

申请号：

US12161733

公开号：

US08771686B2

申请日:

2007.01.26

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present inventors focused on the fact that inflammation at the subretinal macular area enhances choroidal neovascularization, and developed pharmaceutical agents that suppress initiation or advancement of neovascularization by angiogenic factors such as VEGF. More specifically, the present inventors revealed that administering anti-IL-6 receptor monoclonal antibodies to mice treated with laser photocoagulation inhibits the development of choroidal neovascularization.

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