Charles R. Hutchinson,James R. Prudent,Jon S. Thorson
申请号:
US12878775
公开号:
US08470980B2
申请日:
2010.09.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to, inter alia, extracellular drug conjugates (EDC) in which an antibody or other targeting agent (e.g. a targeting moiety) is linked to a drug through a linker (e.g. a non-cleavable linker). These conjugates are useful in the treatment of disease and/or as a tool in the evaluation of biological systems.