Zhengming Chen,Laykea Tafesse,Jiangchao Yao,Khondaker Islam
申请号：
US11991626
公开号：
US08193208B2
申请日:
2006.09.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to fused and spirocycle compounds of Formula I:or a pharmaceutically acceptable salt, prodrug, or solvate thereof, wherein R1, R2, Q1-Q3, and Z are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.
