A reloadable auto injector includes a syringe with a needle movably positioned in a housing between a first position with the needle inside the housing and a second position with the needle protruding outside the housing. A plunger rod advances in the syringe for delivering a dose of medicament. A plunger rod tube having deflectable locking members interacts with a plunger rod stop to lock the plunger rod. A syringe driver moves the syringe from the first position to the second position. The syringe driver advances the plunger rod tube with the plunger rod to the second position. A plunger rod driver advances the plunger rod in the syringe for delivering a dose of medicament upon unlocking each of the deflectable locking members. A reload mechanism retracts the syringe from the second position to the first position and reloads for repeated activation of the syringe driver.