Young Kee Shin,Yoon-La Choi,Young Woo Park,Seung Hyun Lee,Kyoung Song
申请号:
US12307108
公开号:
US08425906B2
申请日:
2007.07.02
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to a method to inhibit cancer by targeting CD24, more precisely a method to inhibit cancer by using CD24 expressed in most cancer cells as a target of an antibody therapeutic agent or by inhibiting the interaction between CD24 and P-selectin. CD24 is over-expressed in most cancer cells and CD24 accumulated in cytoplasm accelerates metastasis. Therefore, the method to inhibit cancer of the invention by targeting CD24 can be effectively used for the treatment of cancer by inhibiting the progress of various cancers over-expressing CD24.