A plant cultivation device includes a case, a temperature control module, and a circulation fan. A cultivation room is formed in the case. The temperature control module includes a piezoelectric chip and a heat exchange assembly. The heat exchange assembly includes a heat conduction plate and multiple fins are formed on the heat conduction plate. One surface of the piezoelectric chip is in the cultivation room and attached on the heat conduction plate. The other surface of the piezoelectric chip is outside of the cultivation room. The circulation fan is attached on the heat exchange assembly. A horizontal component of an airflow direction of the circulation fan (300) is in the same direction as a horizontal component of a normal direction of each fin.