Gabriel A. Mintier,Jian Chen,John N. Feder,Bowman Miao,Rex Arnold Parker
申请号：
US13720000
公开号：
US20130108612A1
申请日:
2012.12.19
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides novel polynucleotides encoding PCSK9b and PCSK9c polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel PCSK9b and PCSK9c polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
