ADENOSINE USED FOR PREVENTION AND TREATMENT OF CENTRAL NERVOUS DISEASE, ADENOSINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND FOODS AND DRINKS CONTAINING ADENOSINE OR ADENOSINE DERIVATIVES
To develop and provide CREB-dependent long-term memory gene transcriptional activity involved in CRE, or substances that promote CRE-dependent long-term memory gene transcription activity, and pharmaceutical compositions and foods and drinks containing these.SOLUTION: The adenosine or adenosine derivatives of the present invention are used for the prevention and treatment of central nervous disease to promote CREB-dependent long-term memory gene transcriptional activity involved in CRE, or CRE-dependent long-term memory gene transcriptional activity.SELECTED DRAWING: Figure 1【課題】ＣＲＥに関与するＣＲＥＢ依存性長期記憶遺伝子転写活性、又はＣＲＥ依存性長期記憶遺伝子転写活性を促進する物質、及びこれらを含む医薬組成物や飲食物を開発するために、を提供する。【解決手段】アデノシン又はアデノシン誘導体は、中枢神経疾患の予防及び治療に用いられ、ＣＲＥに関与するＣＲＥＢ依存性長期記憶遺伝子転写活性、又はＣＲＥ依存性長期記憶遺伝子転写活性を促進する。【選択図】図１
