A medical device may include an elongate shaft having a distal end portion and a balloon disposed at least partially within the distal end portion. The distal end portion may be configured to selectively expand from a collapsed delivery configuration to a distally-opening expanded filtering configuration. A method of deploying a medical device may include obtaining an elongate shaft having a distal end portion and a balloon disposed at least partially within the distal end portion, advancing the elongate shaft through a vessel to a treatment site, disposing at least a portion of the balloon within the treatment site with the distal end of the elongate shaft positioned adjacent the treatment site, at least partially inflating the balloon, thereby expanding the distal end portion, and deflating the balloon and subsequently performing a procedure with the distal end of the elongate shaft positioned within the vessel adjacent to the treatment site.