A fundus photographing apparatus with wavefront compensation, includes: a fundus photographing optical system (100) for capturing a fundus image by receiving a reflected light from fundus of an examinees eye a wavefront compensation device (72) placed in an optical path of the fundus photographing optical system to compensate a wavefront aberration of the examinees eye by controlling an incident light wavefront and a wavefront aberration detection optical system (110) for projecting a measurement light on the fundus of the examinees eye to detect a reflected light of the measurement light from the fundus using a wavefront sensor (73), characterized in a controller (80) for controlling an effective region (41, 62) formed on the wavefront compensation device so as to correct a difference between the effective region formed on the wavefront compensation device where an aberration correction control is effective and a wavefront measurement region (61) of the wavefront aberration detection optical system where the wavefront aberration is measured.