Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.6,7-二氫-5H-咪唑并[1,2-a]咪唑-3-羧酸醯胺之衍生物係在CAM與白整合素之交互作用時顯示良好抑制作用,且因此可用於治療炎性疾病。