The present invention is directed to 4-methylsulfonyl-2-butenenitrile, or a pharmaceutically acceptable salt, an isomer, or isomers thereof. The present invention is also directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and 4-methylsulfonyl-2-butenenitrile, or a pharmaceutically acceptable salt, an isomer, or isomers thereof. The present invention is directed to a method for treating inflammation, inflammatory-related disorders, or pain, by administering 4-methylsulfonyl-2-butenenitrile, or a pharmaceutically acceptable salt or solvate thereof to a subject in need thereof.