THORNTON, Arnold W.,KIM, Dennis Dong-Won,KNUDSON, Mark B.,TWEDEN, Katherine S.,WILSON, Richard R.
申请号:
AU2014202313
公开号:
AU2014202313A1
申请日:
2014.04.29
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2014202313A120140522.pdf#####ABSTRACT OF THE DISCLOSURE Various methods and apparatus for treating a condition associated with impaired glucose regulation in a subject comprising in one embodiment, applying a neural conduction block to a target nerve at a blocking site with the neural 5 conduction block selected to at least partially block nerve pulses. In another embodiment, combinations of down-regulating and or up-regulating with or without pharmaceutical agents are used to treat impaired glucose regulation. In other embodiments, up-regulation or down-regulation of various nerves, such as the vagus and its branches, and the splanchnic is used to modify the production of GLP-1 and 10 GIP, thereby controlling glucose levels. In yet further embodiments, combinations of down-regulating and or up-regulating with or without pharmaceutical agents are used to modify the production of GLP-1 and GIP, to treat impaired glucose regulation. 63 5323399 1 (GHMatters) P85213.AU.1