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Repeat Protein Conjugates of iL4 / IL13 and its uses
专利权人:
JANSSEN BIOTECH, INC.;MOLECULAR PARTNERS;JANSSEN BIOTECH; INC.
发明人:
JACOBS STEVEN,KARYN O'NEIL,BAUMANN MICHAEL,SENNAUSER GABY,KARYN ONEIL
申请号:
UY34048
公开号:
UY34048A
申请日:
2012.04.30
申请国别(地区):
UY
年份:
2012
代理人:
摘要:
Binding proteins comprising Union / IL13 iL4 domains which inhibit iL4, IL13 / Union to il4ralpaha Complex Common gamma Chain (Type 1) s and inhibit the binding of complexes il4ralpha iL4 and il13ralphal (Type 2), and the Union of IL13 to il13ralphal and / or il13ralpha2 are useful In the treatment of inflammatory diseases, cancer and other Pathological conditions.Conditions such as allergic or fibrotic Lung diseases, especiallyLas proteínas de unión a IL4/IL13 comprenden dominios de unión, que inhiben la unión de IL4/IL13 a IL4Ralpaha y complejos de cadena gamma comunes (Tipo 1) s e inhiben la unión de IL4 a complejos de IL4Ralpha y IL13Ralphal (Tipo 2), y la unión de IL13 a IL13Ralphal y/o IL13Ralpha2, son útiles en el tratamiento de cáncer, enfermedades inflamatorias y otras enfermedades patológicas, tales como condiciones alérgicas o fibróticas, especialmente enfermedades pulmonares
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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