An ankle brace is provided, including a main body. The main body has a base portion and an abutting portion for abutting against an ankle, the base portion has at least one first guiding slot, the at least one first guiding slot is arranged next to the abutting portion, the abutting portion has a bottom portion, a circumferential side portion which surrounds and is connected to and between the bottom portion and the base portion and at least one second guiding slot, the bottom portion has a receiving space for receiving a part of the ankle, the circumferential side portion projects above a slot bottom of the first guiding slot, and the at least one second guiding slot is arranged on the bottom portion and penetrates the circumferential side portion and communicated with the at least one of the first guiding slots.