The invention provides an antibody binding to Ly75. A nucleic acid molecule encoding the antibody, an expression vector, a host cell and a method for expressing the antibody are also provided. The antibody can be used to treat cancer, including pancreatic cancer, ovarian cancer, breast cancer, colorectal cancer, esophageal cancer, skin cancer, thyroid cancer, lung cancer, bladder cancer, multiple myeloma and lymphoma.本發明提供了結合LY75的抗體。也提供編碼該抗體的核酸分子，用於表達該抗體的表達載體、宿主細胞和方法。該抗體可用於治療癌症，包括胰腺癌、卵巢癌、乳腺癌、結直腸癌、食道癌、皮膚癌、甲狀腺癌、肺癌、膀胱癌、多發性骨髓瘤和淋巴瘤。
