PROTEÍNAS DE FUSÃO LLO NÃO HEMOLÍTICAS E MÉTODOS PARA A SUA UTILIZAÇÃO

• 收藏
• 分享

专利权人:

THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

发明人:

YVONNE PATERSON,PAULO MACIAG

申请号：

PT09798450

公开号：

PT2307049T

申请日:

2009.06.22

申请国别(地区):

PT

年份:

2017

代理人:

摘要：

A recombinant protein comprising a listeriolysin O (LLO) protein, wherein the LLO protein comprises a mutation, or deletion of 2-11 amino acid residues within the cholesterol-binding domain (CBD) of the LLO protein, and wherein the recombinant protein exhibits a greater than 100-fold reduction in hemolytic activity relative to wild-type LLO. The recombinant protein may further comprise a heterologous peptide, such as an antigenic peptide.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/