NOVOS ÁCIDOS NUCLEICOS QUE SE LIGAM A C5A

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专利权人:

APTARION BIOTECH AG

发明人:

申请号：

PT13700617

公开号：

PT2802660T

申请日:

2013.01.10

申请国别(地区):

PT

年份:

2020

代理人:

摘要：

The present invention is related to a nucleic acid molecule capable of binding to human C5a, wherein the nucleic acid molecule comprises a central stretch of nucleotides, wherein the central stretch of nucleotides comprises a nucleotide sequence of 5′ AUGn1GGUGKUn2n3RGGGHUGUKGGGn4Gn5CGACGCA 3′ [SEQ ID NO: 61], wherein n1 is U or dU, n2 is G or dG, n3 is A or dA, n4 is U or dU, n5 is U or dU and G, A, U, C, H, K, and R are ribonucleotides, and dU, dG and dA are 2′-deoxyribonucleotides.

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