PROBLEM TO BE SOLVED: To provide a compound having a new working mechanism which is effective to treatment of NASH, and to provide a medical use thereof.SOLUTION: This invention relates to an urea derivative represented by general formula (I) or its pharmacologically acceptable salt. [In the formula, A is a substituent represented by general formula (IIa) or (IIb), and R is a hydrogen atom, a halogen atom, 1-4C alkoxy, or 6-12 aryloxy which may have a substituent]. (In the general formula (IIb), R is a hydrogen atom, a halogen atom, 1-4C alkoxy, or 6-12 aryloxy which may have a substituent).COPYRIGHT: (C)2013,JPO&INPIT【課題】NASHの治療に有効な新規な作用メカニズムを有する化合物及びその医薬用途を提供すること。【解決手段】本発明は、下記の一般式(I)で表される尿素誘導体又はその薬理学的に許容される塩を提供する。【選択図】なし
