BOLLBUCK, BIRGIT,MARKERT, CHRISTIAN,MILTZ, WOLFGANG,ROEHN, TILL
申请号：
TW104119643
公开号：
TWI670262B
申请日:
2015.06.17
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
The present invention describes novel heteroaryl butanoic acid derivatives that are good drug candidates especially with regard to leukotriene A4 hydrolase (LTA4H). The present invention also relates to pharmaceutical compositions comprising said novel heteroaryl butanoic acid derivatives, methods of using said compounds in the treatment of various diseases and disorders, and processes for preparing the said novel compounds.本發明闡述新穎雜芳基丁酸衍生物，該等尤其係關於白三烯A4水解酶(leukotriene A4 hydrolase；LTA4H)之優良藥物候選者。本發明亦係關於包含該等新穎雜芳基丁酸衍生物之醫藥組合物、使用該等化合物治療各種疾病及病症之方法，及製備該等新穎化合物之製程。
