benzofuran compounds

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

JUERGEN WICHMANN,ROSA MARIA RODRIGUEZ SARMIENTO

申请号：

BR112013014770

公开号：

BR112013014770A2

申请日:

2011.12.12

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

The present invention is concerned with novel dual modulators of the 5-HT2A and D3 receptors of formula (I) wherein n, x, Y, R1, R2, R3, and R4 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions comprising them and their use as pharmaceuticals.

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