Zhehong CAI,Indrani CHAKRABORTY,Marie-Michelle Navarro GARCIA,Thomas D. KEMPE,Alan J. KORMAN,Alexander T. KOZHICH,Hadia LEMAR,Mark MAURER,Christina Maria MILBURN,Michael QUIGLEY,Maria RODRIGUEZ,Xiang
申请号:
US15577375
公开号:
US20180237534A1
申请日:
2016.05.26
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are antibodies, or antigen binding portions thereof, that bind to OX40. Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.