Marcos Rafael Oggero Eberhardt;Ricardo Kratje;Ricardo Agustin Lopez;Marina Etcheverrigaray;Natalia Analia Ceaglio
发明人:
Ricardo Agustin Lopez,Natalia Analia Ceaglio,Marina Etcheverrigaray,Marcos Rafael Oggero Eberhardt,Ricardo Kratje
申请号：
US12306056
公开号：
US20120134960A1
申请日:
2007.06.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A recombinant human interferon-alpha mutein that contains at least one glycosylation site at a position of its amino acid sequence that is a part of an alpha helix-type secondary structure, a gene encoding the mutein, a method for producing the gene, a method for obtaining an eukaryotic cell producing the mutein, a method for producing the mutein, a process for purifying the mutein, a pharmaceutical composition containing the mutein, and the use of the mutein for manufacturing a medicament.
