The present invention provides a kind of Nerve Scaffolds of base what muscle, and including the degradable metal wire that bracket coating materials and bracket coating materials wrap up, the bracket coating materials is muscle and nerve growth factor (NGF). The Nerve Scaffold and preparation method thereof of the base what muscle, the Nerve Scaffold provide growth, maturation and the microenvironment functioned for fracture nerve, have three-dimensional structure and NGF required for nerve regneration, have far-reaching significance to neural restoration.本發明提供了一種基於肌肉的神經支架,包括支架膜料以及支架膜料包裹的可降解金屬絲,所述支架膜料爲肌肉和神經生長因子(NGF)。所述基於肌肉的神經支架及其製備方法,所述神經支架爲斷裂神經提供了生長、成熟和發揮功能的微環境,具有神經再生所需要的三維結構和NGF,對神經修復具有深遠的意義。