Medical devices such as ureteral stents, and methods of use thereof are disclosed. The medical device may include an elongate member configured to be implanted within a patient's body, wherein the elongate member includes an outermost diameter and a plurality of support members disposed within a biodegradable matrix. Degradation of the biodegradable material may result in a reduction of size of the medical device. Some or all of the support members, such as at least two of the support members, may be arranged non-concentrically.