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TIMBRE D'ABSORPTION TRANSDERMIQUE DE MÉDICAMENT ANTIVIRAL ET SON PROCÉDÉ DE PRÉPARATION
专利权人:
WUHAN UNIVERSITY
发明人:
WANG, YEFU,LI, WEI,ZHOU, XIAOZHOU
申请号:
EP10838390
公开号:
EP2606895A4
申请日:
2010.10.12
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
An antiviral transdermal absorbing patch includes a backing layer, a viscous polymer layer, and a protection film layer. The viscous polymer layer includes an antiviral agent, a viscous polymer, and a transdermal enhancer. The transdermal enhancer is laurocapram or a mixture thereof. The antiviral agent is a nucleoside antiviral drug with a daily delivery rate of less than 100 mg/day. A method for producing the patch is also provided. The antiviral transdermal absorbing patch effectively promotes the penetration of a nucleoside antiviral agent into skin and then the agents is assimilated via capillary vessels and enters the blood circulation, thereby inhibiting the replication of target viruses and reducing viral DNA level in the serum, and administrating sustainably and stably. In addition, the transdermal administration avoids the enzymolysis of gastrointestinal tract and the first pass effect of the liver and reduces toxicity and side effect of drugs. The raw materials involved in the invention are simple and available from the marke , with a low cost, which enable the patch to have the great practibility.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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