DUBENSKY, THOMAS, W.,BROCKSTEDT, DIRK, G.,LEONG, MEREDITH,BAHJAT, KEITH, S.
申请号:
EP11787200
公开号:
EP2576791A4
申请日:
2011.05.23
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Provided herein are prime-boost regimens and materials used therein. The prime-boost regimens enhance the immune response to a target antigen. The vaccines used for boost are comprised of recombinant attenuated metabolically active Listeria that encodes an expressible antigen that is cross-reactive with the target antigen. In some examples, the immune response is a cellular immune response.