The present invention is directed to compositions for the sustained delivery of antibiotic, for example vancomycin, to achieve desirable release profile. This application is also directed to methods of using the compositions and processes for manufacturing the compositions.本發明係關於抗生素,例如萬古黴素(vancomycin),持續性遞送以達到合宜的釋放型態(release profile)用之組合物。本申請案也有關使用該組合物的方法與製造該組合物之方法。