STEENDAM ROB,FLIPSEN THEODORUS ADRIANUS CORNELIUS,HIEMSTRA CHRISTINE,ZUIDEMA JOHAN
申请号：
IN300/MUMNP/2014
公开号：
IN2014MN00300A
申请日:
2014.02.17
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
This invention is directed to a biodegradable semi crystalline phase separated thermoplastic multi block copolymer a process for preparing said multi block copolymer a composition for the delivery of at least one biological active compound and to a method for delivering a biologically active compound to a subject in need thereof. A multi block copolymer of the invention is characterised in that: a) it comprises at least one hydrolysable pre polymer (A) segment and at least one hydrolysable pre polymer (B) segment b) said multi block copolymer having a T of 37 °C or less and a Tm of 110 250 °C under physiological conditions c) the segments are linked by a multifunctional chain extender d) the segments are randomly distributed over the polymer chain e) at least part of the pre polymer (A) segment is derived from a water soluble polymer.
