PARADISO, PETER, R.,PRASAD, A., KRISHNA,SIBER, GEORGE, RAINER,HAUSDORFF, WILLIAM, P.
申请号:
DK07865465
公开号:
DK2094304T3
申请日:
2007.12.10
申请国别(地区):
DK
年份:
2016
代理人:
摘要:
An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) conjugated to a carrier protein. The immunogenic composition, formulated as a vaccine, increases coverage against pneumococcal disease in infants and young children globally, and provides coverage for serotypes 6A and 19A that is not dependent on the limitations of serogroup cross-protection.