A guide for an endoscope capsule includes a hollow sleeve. The distal end of the sleeve has attached an invertible member for fitting the capsule within. The invertible member may be inverted via hydraulic or pneumatic pressure to expel the capsule from the guide and into a desired location within a patients body lumen. The guide may be attached to an actuator which contains a fluid and an actuating member. The actuating member pressurizes the fluid distally through the hollow sleeve thereby inverting the invertible member and expelling the capsule into the body lumen. The guide may be used with an endoscope or may be a stand-alone device.