It is provided a combination comprising diaminopyrimidine oxide, oleanolic acid, biotinoyl tripeptide-1, apigenin, biotin, adenosine or an adenosine derivative, and Gingko biloba, a topical composition comprising a therapeutically effective amount of the combination together with appropriate topical cosmetically or pharmaceutically acceptable excipients or carriers. It is also provided the composition for use in reducing or preventing the loss of hair and/or stimulating its growth.
