NAVIDEA BIOPHARMACEUTICALS, INC.;OHIO STATE INNOVATION FOUNDATION
发明人:
Frederick O. Cope,Michael S. Blue,Wendy L. Metz,Larry S. Schlesinger
申请号：
US14338332
公开号：
US20150023876A1
申请日:
2014.07.22
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A method of diagnosing a CD206 expressing cell-related disorder by administering a pharmaceutical composition to a subject, the composition including a carrier molecule having a detectable moiety attached thereto. The carrier molecule has a dextran backbone, and at least one receptor substrate conjugated, directly or indirectly, to the dextran backbone, wherein the receptor substrate is chosen so as to specifically bind to CD206. A method of treating a CD206 expressing cell-related disorder is also provided, as well as an ex vivo method and kit for quantitating the number of cells expressing CD206 in a bodily fluid.
