Method and the composition which remedy a state where it is annexed to the metabolism characteristic disease and the metabolism characteristic disease, are offered in this bill.< Selective figure >Figure 1A and figure 1B代謝性疾患及び代謝性疾患に付随する状態を治療する方法及び組成物が、本明細書において提供される。【選択図】図1A、図1B