CHOI JANG-SIK,SONG HO-JUHN,KIM HONG WOO,LIM SUN-HEE,KIM YOUNGSAM,LEE JAEKYOO,KOH JONG SUNG,CHANG SUNHWA,LEE HEE KYU
申请号:
NZ63086010
公开号:
NZ630860A
申请日:
2010.10.29
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Disclosed are bi-substituted -amino-pyrido[4,3-d]pyrimidine-5(6H)-one derivatives as represented by the general formula (I), wherein the variables are as defined in the specification. These compounds are suitable for treating neurodegenerative disease such as Parkinson&rsquos disease or Alzheimer&rsquos disease, and inflammatory disease selected from asthma, chronic obstructive pulmonary disease (COPD), adult respiratory distress syndrome (ARDs), ulcerative colitis, Crohn&rsquos disease, bronchitis, dermatitis, allergic rhinitis, psorasis, scleroderma, urticaria, rheumatoid arthritis, multiple sclerosis, or cancer.