The present invention relates to bicyclic heterocycle and its pharmaceutical compositions, are the inhibitor of one or more FGFR enzymes and are suitable for treatment FGFR related disease, such as cancer.本發明涉及雙環雜環及其藥物組合物,其爲一種或多種FGFR酶的抑制劑且適用於治療FGFR相關疾病,諸如癌症。