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Process for preparing A 3-pyrrole substituted 2-indolinone malate salt
专利权人:
Bernardino Mangion
发明人:
Bernardino Mangion,Stephen Benedict David Winter
申请号:
US12483856
公开号:
US08153678B2
申请日:
2009.06.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to the malic acid salt of N-[2-(diethylamino)ethyl]-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide, to the use thereof as an intermediate for preparing the malic acid salt of sunitinib, and to pharmaceutical compositions comprising said malic acid salt of sunitinib.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关专利
CRYSTALS INCLUDING A MALIC ACID SALT OF N-[2-(DIETHYLAMINO)ETHYL]-5-[(5-FLUORO-2-OXO-3H-INDOLE-3-YLIDENE) METHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE, PROCESSES FOR ITS PREPARATION AND COMPOSITIONS THEREOF
Crystals including a malic acid salt of N- [2- (diethylamino) ethyl] -5 - [(5-fluoro-1,2-dihydro-2-oxo-3H-indole-3-ylidene) methyl] -2 , 4-dimethyl-1H-pyrrole-3-carboxamide, processes for its preparation and its compositions
Crystals including a malic acid salt of n-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-3h-indole-3-ylidene)methyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide, processes for its preparation and compositions thereof
Crystals containing a malic acid salt of N- [2- (diethylamino) ethyl] -5 - [(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene) methyl] -2,4-dimethyl -1H-pyrrole-3-carboxyamide, processes for their preparation and compositions thereof
CYCLOALKENE DICARBOXYLIC ACID COMPOUNDS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND USES THEREOF IN THE PREPARATION OF MEDICAMENTS