In one embodiment, a neurostimulation system for stimulating neuronal tissue of a brain of a patient, comprises: an implantable pulse generator comprising pulse generating circuitry and a controller one or more stimulation leads comprising multiple electrodes, the implantable pulse generator adapted to connect to the one or more stimulation leads for delivery of generated electrical pulses to neuronal tissue of the patient wherein the controller is adapted to control the implantable pulse generator to (i) generate a plurality of bursts of multiple pulses at a frequency of at least 100 Hz and (ii) to deliver each respective bursts on a randomly or pseudo-randomly selected electrode from multiple electrodes of the one or more stimulation leads, wherein a beginning of each burst in the plurality of bursts is separated from a beginning of its respective successive bursts by at least 50 milliseconds.
