SCALES, CHARLES W.,史考利 查尔斯,史考利 查爾斯,GEORGE, ERIC R.,乔治 埃里克,喬治 埃里克,ANDERSON, CHRISTOPHER D.,安德森 克里斯托弗,安德森 克里斯托弗,GLEIM, ROBERT D.,葛兰 罗伯特,葛蘭 羅伯特,HEALY, BRENT MATTHEW,希利 布伦特马太,希利 布倫特馬太
申请号：
TW101145981
公开号：
TW201337314A
申请日:
2012.12.07
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
Provided are compositions containing engineered particles, and methods of making such engineered particles. Polymeric articles, such as contact lenses, prepared from such compositions are also provided. Such engineered particles are dispersible in hydrophilic systems such as monomer systems for preparation of contact lenses. Each of the engineered particles comprises a hydrophobic core and a hydrophilic shell. The hydrophobic core comprises a silicone-based polymer that can have multiple cross-links and/or polymer-polymer entanglement, and the hydrophilic shell is formed from a reactive stabilizer. A residue of the reactive stabilizer or a hydrophilic segment of the reactive stabilizer can form the shell. The particles have an average particle size of less than about 500 nm.所提供者為含工程粒子之組成物,以及製造此類工程粒子之方法。亦提供由此類組成物製成之聚合性物件如隱形眼鏡。此類工程粒子可分散於親水性系統如單體系統中以製備隱形眼鏡。各個工程粒子包含一疏水性核與一親水性殼。該疏水性核包含一以聚矽氧為主的聚合物,該聚合物可具有多個交聯與/或聚合物-聚合物纏結,並且該親水性殼係由一反應性穩定劑形成。該反應性穩定劑之一殘基或該反應性穩定劑之一親水性片段可形成該殼。該粒子之平均粒徑小於約500 nm。
