ТИНГ Энтони Е. (US);ДИНС Роберт Дж. (US);ЛАФРАНЧЕСКА Саверио (US)
发明人:
ЛАФРАНЧЕСКА Саверио (US),ТИНГ Энтони Е. (US),ДИНС Роберт Дж. (US)
申请号：
RU2018130072
公开号：
RU2018130072A
申请日:
2014.04.14
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
The invention provides methods and compositions that improve the success of organ transplantation. The methods and compositions are directed to exposing a desired organ to stem cells prior to, during, and/or after transplantation. In one embodiment, the stem cells reduce the deleterious effects of ischemia on an organ designated to be harvested for transplantation or that has been harvested for transplantation. In another embodiment in which an organ designated for transplantation is perfused ex vivo, the method involves reducing ischemic reperfusion injury by perfusing the organ with a medium that contains stem cells.
