Adamantyl derivatives as inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme

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专利权人:

AbbVie Inc.

发明人:

Sorensen, Bryan K.,Yong, Hong,Link, James T.,Rohde, Jeffrey J.,Yeh, Vince S.,Patel, Jyoti R.,Winn, Martin,Shuai, Qi,Dinges, Jurgen

申请号：

AU2011253958

公开号：

AU2011253958B2

申请日:

2011.12.12

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2011253958B220130627.pdf#####ADAMANTYL DERIVATIVES AS INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME Abstract The present invention relates to compounds which are inhibitors of the 11 -beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of I 1-beta-hydroxysteroid dehydrogenase Type I enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action. (5788716_I):KZA

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