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Tetrary gene delivery system for gene therapy and methods of its use
专利权人:
Peisheng Xu
发明人:
Peisheng Xu,Remant Bahadur K.C.
申请号:
US13477701
公开号:
US09168230B2
申请日:
2012.05.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Delivery systems and their methods of formation are generally provided. The delivery system can protect a delivery molecule (e.g., DNA/RNA) and deliver it into a cell via serum. In one embodiment, the method can include binding a delivery molecule with polyethylenimine such that an end of the delivery molecule is exposed capping the end of the delivery molecule with a first biocompatible polymer to form a core and encapsulating the core with a second biocompatible polymer. The resulting delivery system can include a delivery molecule bonded with polyethylenimine such that an end of the delivery molecule is exposed a first biocompatible polymer electrostatically bonded to the end of the delivery molecule to form a core and a second biocompatible polymer encapsulating the core.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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