Campbell, Carey V.,Cleek, Robert L.,Cully, Edward H.,Heicksen, Peter,Holland, Theresa A.,Kranzler, Thane L.,Li, Mei,Steinhaus, Bruce M.,Trapp, Benjamin M.,Triebes, Thomas G.,Vonesh, Michael J.
申请号：
AU2013312748
公开号：
AU2013312748A1
申请日:
2013.09.05
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The invention is directed to delivery medical devices that enable consistent "on-demand" delivery of therapeutic agents to a vessel. The medical device of the current invention comprises retractable sheath comprising neckable elements. The medical device of the current invention comprises an expandable member, a hydrophilic coating comprising at least one therapeutic agent about the expandable member or structural layer and a retractable outer sheath with a selectively permeable microstructure. The design and methods disclosed herein ensures that therapeutic agent delivery occurs essentially only during retraction of the outer sheath, minimizing coating and/or therapeutic agent loss to the bloodstream and providing controlled delivery to the treatment site.
