Walter, Korden,Kreuzberg, Maria,Erdeljan, Michael,Koslowski, Michael,Tureci, Ozlem,Woll, Stefan,Hubner, Bernd,Sahin, Ugur
申请号:
NZ73430710
公开号:
NZ734307A
申请日:
2010.11.11
申请国别(地区):
NZ
年份:
2020
代理人:
摘要:
Disclosed an anti-CLDN6 antibody or an antigen binding fragment thereof as defined wherein the heavy chain variable region is covalently linked to the light chain variable region. Further disclosed are recombinant nucleic acids encoding said antibodies or antigen binding fragments thereof and methods of producing said antibodies comprising the steps of culturing a host cell transformed with expression constructs comprising a nucleic acid sequence encoding an antibody heavy chain variable region and light chain variable region and harvesting a preparation of the antibody or antigen binding fragment thereof expressed by the cell.