Provided herein are antigen-binding proteins (ABPs) that selectively bind to TIGIT and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods.本文提供選擇性結合至TIGIT及其同型及同系物之抗原結合蛋白(ABP),及包含該等ABP之組合物。本文亦提供使用該等ABP之方法,如:治療及診斷方法。