A device and method for polymer modification of biological cells includespumping a first liquidmixture comprising biological cells from a first reservoir to a mixing chamberand a secondliquid mixture comprising activated polymer from a second reservoir to thesame mixingchamber, independently controlling an output volume of the first and secondliquid mixturespumped into the mixing chamber using at least one pump, mixing the first andsecond liquidmixtures in the mixing chamber to produce a final mixture comprising polymer-modifiedbiological cells, and evacuating the final mixture comprising polymer-modifiedbiological cellsfrom the mixing chamber into an output reservoir.